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第116回WPI-IIISセミナー

2017/08/23

日 時:平成29年8月23日(水) 12:00-13:00

場 所:筑波大学 医学系エリア 睡眠医科学研究棟 1F 講堂 GooglrMap版へ
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利用停留所(関東鉄道バス):筑波大学中央行き又は筑波大学循環バス「追越学生宿舎前

演 者: Dr. Hiroaki Wake(和氣 弘明 先生)
     Kobe University Graduate School of Medicine  (神戸大学大学院医学研究科)

演 題:“Activity dependent myelin regulation in information processing“

要 旨: Myelination increases conduction velocity and promotes brain functions. Myelin dysregulation is frequently associated with learning and cognition deficits, ultimately causing psychiatric disorders.
Although we have been identified the underlying molecular mechanisms of activity-dependent myelination, the nature of the neural activity changes and the behavior output caused by myelin dysregulation remains unknown. In this research, we visualized neural activity in the motor cortex during motor learning using in vivo two photon microscope to understand the abnormality of neural activity associated with impaired behavior output with myelin dysregulation. We further demonstrate the optogenetic stimulation to compensate the abnormal activity of neural activity to rescue the learning disability.

問い合わせ:国際統合睡眠医科学研究機構 029-853-8080(内線8080)

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