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第155回WPI-IIISセミナー

2019/07/24

日 時:2019年7月24日(水) 12:00-13:00

場 所:筑波大学 医学系エリア 睡眠医科学研究棟 1F 講堂GooglrMap版へ
アクセス:「筑波大学筑波キャンパスへの交通アクセス」をご覧ください。
利用停留所(関東鉄道バス):筑波大学中央行き又は筑波大学循環バス「追越学生宿舎前

演者: Dr. Paul Frankland
    Hospital for Sick Children Research Institute / University of Toronto

演題: “Reconfiguring memory networks for long-term consolidation”

要旨: While memories for events may initially depend on the hippocampus, over time they are reorganized in the cortex for long-term storage. Our studies have identified brain-wide networks engaged in memory recall at both recent and remote time points. Using chemogenetic approaches to interrogate these networks, we subsequently showed that hub brain regions within these networks disproportionately influence memory consolidation. In our most recent work, we have focused on the role of white matter plasticity in memory consolidation. Our studies indicate that white matter plasticity is required for learning-induced coupling of hippocampal sharp-wave ripples and cortical spindles and successful memory consolidation. Therefore, these results identify a non-neuronal form of plasticity that fine tunes hippocampal-cortical networks following learning and is required for memory consolidation.

詳細はこちらからもご覧になれます

http://wpi-iiis.tsukuba.ac.jp/japanese/seminar

問い合わせ

国際統合睡眠医科学研究機構
029-853-8080(内線8080)

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