*This seminar will be held in English.
|Date / Time||Wednesday, August 23, 2017 12:00-13:00|
|Place||1F Auditorium, IIIS Building, University of Tsukuba|
|Access||Take a bus bound for "Tsukuba Daigaku Chuo" or the "University Loop-line On-campus Bus [Tsukuba Daigaku Junkan Bus]" and get off at Oikoshi Gakusei Shukusha Mae|
|Speaker||Dr. Hiroaki Wake
Kobe University Graduate School of Medicine
|Subject||"Activity dependent myelin regulation in information processing"|
|Summary||Myelination increases conduction velocity and promotes brain functions. Myelin dysregulation is frequently associated with learning and cognition deficits, ultimately causing psychiatric disorders.
Although we have been identified the underlying molecular mechanisms of activity-dependent myelination, the nature of the neural activity changes and the behavior output caused by myelin dysregulation remains unknown. In this research, we visualized neural activity in the motor cortex during motor learning using in vivo two photon microscope to understand the abnormality of neural activity associated with impaired behavior output with myelin dysregulation. We further demonstrate the optogenetic stimulation to compensate the abnormal activity of neural activity to rescue the learning disability.
|Contact||International Institute for Integrative Sleep Medicine
Phone: 029-853-8080 (ext.8080)
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