This seminar will be held in English.
This seminar is one of the seminars for the subject "Seminar in Medical Sciences" in Doctoral Programs in Biomedical Sciences and Clinical Sciences.
|Date / Time||October 12 (Thu) 15:00-17:00|
|Place||4A Building, Medical Area, University of Tsukuba|
|Access||Take a bus bound for "Tsukuba Daigaku Chuo" or the "University Loop-line On-campus Bus [Tsukuba Daigaku Junkan Bus]" and get off at Tsukuba Daigaku Byoin Iriguchi.|
|Speaker||Dr. Lih Ling-Lin
Head of Innate Immunity of Inflammation and Immunology Research Unit in Pfizer)
|Seminar Title||Targeting Innate Immunity in Treating Autoimmune and Inflammatory Diseases|
|Abstract||Innate immune system detects danger signals derived from microbial products and endogenous ligands. These danger signals can initiate and perpetuate inflammation and autoimmunity via recognition of pattern recognition receptors such as Toll like receptor (TLR). We aim to develop transformative therapies in treating patients with autoimmune and inflammatory diseases by targeting danger signal pathways contributing to key disease mechanisms. IRAK4 is an essential kinase that mediates TLR and IL-1R signaling. We have developed a potent and selective IRAK4 inhibitor with a potential to become a novel and transformative therapy in treating autoimmune diseases such as Rheumatoid Arthritis and Lupus.|
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