• The 165th WPI-IIIS seminar

    01 20, 2020
    Date Monday, January 20, 2020
    Time 12:00 -13:00
    Venue 1F Auditorium, IIIS Building, University of Tsukuba
    Access Take a bus bound for "Tsukuba Daigaku Chuo" or the "University Loop-line On-campus Bus [Tsukuba Daigaku Junkan Bus]" and get off at Oikoshi Gakusei Shukusha Mae
    Speaker Dr. Shinya Oki
    Department of Developmental Biology, Graduate School of Medical Sciences, Kyushu University
    Subject “Data-driven and technical approaches to understand spatial gene regulation”
    Summary Gene expression is precisely regulated by transcription factors and chromatin structures, but their combinatorial actions for cell type-specific expression are not fully understood. Here, I developed a database designated ChIP-Atlas (, which integrates all of public ChIP-seq data (~120,000 experiments). Furthermore, I established a novel spatial genomics technology, named photo-isolation chemistry, which allows to isolate gene expression and epigenetic profiles only from photo-irradiated regions out of whole tissues. Combination of those data-driven and technical approaches will accelerate to gain deeper insight into spatial gene regulatory mechanisms.

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